DNA methylation

Results: 634



#Item
231Epigenetics / Hepatology / Hepatocellular carcinoma / Sorafenib / Hep G2 / DNA methylation / Methylation / Liver cancer / Hypomethylating agent / Biology / Chemistry / Genetics

SGI-110, a novel second generation DNA hypomethylating agent, enhances sorafenib activity and alters the methylation signature of HCC cell lines No[removed]Simone Jueliger1, John Lyons1, Mohammad Azab2 and Pietro Taverna2

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Source URL: astx.com

Language: English
232DNA / DNA methylation / Epigenetics

No[removed]SGI-110, a Novel Subcutaneous (SQ) Second Generation DNA Hypomethylating Agent Achieves Improved Pharmacodynamics (PD), Safety and Pharmacokinetics (PK) in comparison to IV Decitabine (DAC) in a non-human primat

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
233DNA / DNA methylation / Epigenetics / Myelodysplastic syndrome / Hypomethylating agent / Decitabine / Biology / Medicine / Nucleosides / Triazines

ABST # A190 In Vivo Activity of SGI-110, a Novel Hypomethylating Agent for Treatment in Hematology and Solid Malignancies Jason Scholl, David Vollmer, Jared Bearss, Carissa Jones, Virgil McCarthy, Paul Severson, Sanjeev

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
234Epigenomics / Methylation / DNA methylation / Hypomethylating agent / Acute myeloid leukemia / Cellular differentiation / Genetics / Biology / Epigenetics

Abstract No[removed]Identification of Novel Methylation Biomarkers to Predict Clinical Response to SGI-110, a Second Generation Hypomethylating Agent (HMA), in Patients with Acute Myeloid Leukaemia (AML) Simone Jueliger1,

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Source URL: astx.com

Language: English
235Hypomethylating agent / Health / Toxicology / Medicine / Myelodysplastic syndrome / Syndromes

SGI-110, a Novel Second Generation Potent DNA Methylation Inhibitor, In Development for the Treatment of MDS and AML. Preclinical Safety, Pharmacokinetics, and DNA Methylation Results of a Low Volume Subcutaneous (SC) Fo

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Source URL: astx.com

Language: English - Date: 2012-12-13 18:06:00
236Biochemistry / Laboratory techniques / Polymerase chain reaction / Biotechnology / DNA / Real-time polymerase chain reaction / Amplicon / Multiplex / DNA methylation / Biology / Molecular biology / Chemistry

Clinical Epigenetics This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Multiplex bisulfite PCR resequencing of

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Source URL: www.clinicalepigeneticsjournal.com

Language: English
237Philosophy of biology / Lamarckism / Jean-Baptiste Lamarck / Soft inheritance / Inheritance of acquired characteristics / Epigenome / Heredity / Methylation / DNA methylation / Biology / Genetics / Epigenetics

Is Lamarckian evolution relevant to medicine?

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Source URL: www.ncbi.nlm.nih.gov

Language: English
238DNA / Posttranslational modification / Human evolution / DNA methylation / Middle Stone Age / Methylation / Neanderthal / Denisova hominin / Anatomically modern humans / Genetics / Biology / Epigenetics

Researchers create methylation maps of Neanderthals and Denisovans, compare them to modern humans

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Source URL: phys.org

Language: English - Date: 2015-04-13 03:24:39
239Triazines / Epigenetics / Hypomethylating agent / DNA methyltransferase / Decitabine / Azacitidine / DNA methylation / Methylation / Cell culture / Biology / Chemistry / Nucleosides

11th International Congress on Targeted Anticancer Therapies Paris, March 4-6, 2013 IMMUNOMODULATORY ACTIVITY OF SGI-110, A SECOND GENERATION HYPOMETHYLATING

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Source URL: astx.com

Language: English
240Biology / Methylation / DNA methylation / Angiogenesis / Genetics / Epigenetics / Chemistry

Recent Publications 1. An Agarose-based Microfluidic Platform with a Gradient Buffer for 3D Chemotaxis Studies Rikki Haessler, Yevgeniy Kalinin, Melody Swartz, and Mingming Wu Biomedical Microdevice, 4, 827,[removed]Anal

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Source URL: www.cmm.cornell.edu

Language: English - Date: 2012-02-09 09:45:33
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